FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
This product is solely intended for research purposes as a chemical compound. Its designation permits its use exclusively for in vitro testing and laboratory experimentation. All information regarding this product provided on our website is purely educational. By law, any form of bodily introduction of this product into humans or animals is strictly prohibited. It should only be handled by professionals who are licensed and qualified. This product is neither a drug, food, nor cosmetic, and must not be misrepresented, misused, or mislabeled as such.
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CAS42464-96-0
5-Amino-1MQ
20mg Box(2 x 10mg vials)
Purity 99.66% HPLC
RUO Research use only
Not for human or veterinary use.
5-Amino-1MQ (10mg vials)
Price:
$56.00 – $195.00
Vendor:
Allen Biotechnology Co
Quantity (mg)
$56.00
5-AMINO-1MQ
5-Amino-1MQ, also written as 5-amino-1-methylquinolinium, is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in metabolic research. It is studied for its effects on cellular NAD+ availability, adipocyte metabolism and energy expenditure in preclinical models.
Product Format
10mg vials
Vial Size
10mg
Vial Capacity
3 mL
Box Combinations
20mg, 50mg, 100mg
Cost per milligram
$1.95 – $2.80
Multi-vial Purity
99.66%
Endotoxin Screening
PASSED
Heavy Metals Screening
PASSED
Purity Screening
PASSED
Doubly Validated
YES
Independently Tested
YES
Allen Biotechnology Co Manufacturer ID: WF63 Batch ID: AM202648 CAS: 42464-96-0 Molecular Formula:C10H11IN2
Research summaries
For educational purposes only.
NNMT inhibition in diet-induced obesity models
Preclinical work on methylquinolinium NNMT inhibitors, including 5-amino-1-methylquinolinium, reported high membrane permeability and selectivity for NNMT. In cultured adipocytes, NNMT inhibition reduced intracellular 1-methylnicotinamide, increased NAD+ and SAM, and suppressed lipogenesis. In diet-induced obese mice, systemic treatment was associated with reduced body weight, white adipose mass and adipocyte size without changes in total food intake within the study window.
In plain English
5-Amino-1MQ research centers on NNMT inhibition in animal and cellular models, not appetite suppression. The mouse findings are preclinical and do not establish human outcomes.
NNMT, NAD+ salvage and metabolic disease
Review literature summarizes evidence linking NNMT activity to obesity and type 2 diabetes biology. NNMT methylates nicotinamide using S-adenosylmethionine, which can alter NAD+ salvage chemistry, methyl-donor balance, and downstream energy-metabolism pathways. NNMT knockdown or inhibition has been associated with increased energy expenditure and improved insulin-sensitivity markers in animal and cellular studies.
In plain English
The reviews connect 5-Amino-1MQ to the broader NNMT literature; the strongest evidence remains preclinical.
5-Amino-1MQ — Frequently asked questions
What is 5-Amino-1MQ?
5-Amino-1MQ, also written as 5-amino-1-methylquinolinium, is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in metabolic research. It is sold strictly for laboratory research use — not for human or veterinary use.
What purity is this 5-Amino-1MQ?
The catalog specification lists 99.66% HPLC purity. Our testing policy also requires independent endotoxin, heavy-metals and sterility screening. The current certificate table and linked PDF are samples; a production certificate must match the batch ID printed on the vial.
What sizes does 5-Amino-1MQ come in?
5-Amino-1MQ (10mg vials) is offered in 20mg, 50mg, 100mg boxes (2 × 10mg vials, 5 × 10mg vials, 10 × 10mg vials), priced $56.00 to $195.00 — the per-mg cost falls as box size increases.
How should 5-Amino-1MQ be stored?
Keep sealed lyophilized vials refrigerated at 2–8°C away from light (stable 24+ months). After reconstitution with bacteriostatic water, refrigerate and use within the study-validated window, typically 30 days; never freeze reconstituted solution.
Storage details
Lyophilized (as shipped): store refrigerated at 2–8°C away from light. Sealed vials remain stable for 24+ months; short excursions at room temperature during transit do not affect stability.
After reconstitution: store at 2–8°C and use within the study-validated window (typically 30 days with bacteriostatic water). Do not freeze reconstituted solution.
Handling: direct diluent down the vial wall and swirl gently — never shake. Peptide bonds are mechanically fragile in solution.
Light: keep vials in the box or amber sleeve; repeated light exposure accelerates degradation of 5-Amino-1MQ.
Reviews
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Testing policy and sample certificates
Every saleable batch of 5-Amino-1MQ must have third-party certificates. The values and linked PDF below are samples, not documents for a current saleable batch. A production certificate must match the batch ID printed on the vial.
NOTICE: All information provided above is strictly for educational and informational purposes. These products are research chemicals intended exclusively for laboratory research. They are not approved for human consumption; do not ingest them.
By purchasing from Allen Biotechnology Co, you acknowledge that you are acquiring research chemicals. Only qualified and licensed professionals may handle this product.
Under no circumstances may this product be used as a drug, agricultural product, pesticide, food additive or household chemical. Misrepresenting it for any of those purposes is strictly prohibited by law. All website content is provided for educational use exclusively. Any form of introduction into the human or animal body is illegal.
Independent testing standards with batch-matched documentation.
Allen Biotechnology Co publishes its testing policy, provides a labeled sample certificate, and offers direct research support.
